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Using High-Yield UWorld-Integrated Lectures

Prepare smarter with structured, high-yield recorded lectures and detailed UWorld MCQ explanations. Our subscription-based learning system gives you flexible access to a complete USMLE study pathway.

We help you master USMLE

Structured study pathways, high-yield lectures and detailed MCQ explanations
149.4 Hours

Of High‑Yield Lectures

3600+ MCQs

UWorld MCQs Explained

Online Quiz

Structured System Quiz

92%+

Score Improvement Rate

Begin Your Journey

NextGen USMLE Step 1 — Complete UWorld Mastery Program

Focus on hormone feedback loops and endocrine pathology (thyroid, adrenal, pituitary). Link pharmacology (insulin, steroids, antithyroid meds) with mechanisms of action. Practice clinical correlations — DKA vs HHS, Cushing vs Addison.
 

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Master cardiac physiology — preload/afterload, pressure–volume loops, murmurs. Integrate with ECG interpretation, valvular lesions, and pharmacology (beta-blockers, ACE inhibitors, anti-arrhythmics). Emphasize pathophysiology links with hypertension and heart failure.

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Understand nephron physiology and acid-base regulation. Review nephritic vs nephrotic syndromes, diuretic mechanisms, and electrolyte imbalances. Tie into hypertension management and chronic kidney disease.

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RBC disorders (anemias, hemoglobinopathies) and WBC malignancies (leukemias, lymphomas). Review coagulation cascades, platelet disorders, and transfusion medicine. Integrate with oncology pharmacology (chemotherapy side effects).

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Cover lung volumes, gas exchange, and oxygen dissociation curve. Distinguish obstructive vs restrictive patterns and related diseases (COPD, asthma, fibrosis). Integrate pharmacology of bronchodilators and corticosteroids.

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Review innate vs adaptive immunity, hypersensitivity types, and complement pathways. Master cytokines and immune cell markers (CDs). Relate immunodeficiencies and autoimmune disorders to real-world examples.

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Muscles, bones, and connective tissue — key for anatomy and pathology. Focus on rheumatologic conditions (RA, SLE, gout) and related pharmacology. Remember fracture healing and bone remodeling pathways.

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Master neuroanatomy localization and neurotransmitter pathways. Learn CNS pharmacology (antiepileptics, antidepressants, antipsychotics). Review demyelinating diseases, strokes, and neurodegenerative disorders.

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Digestive physiology, absorption, and hepatobiliary system. Pathology: peptic ulcer, IBD, liver disease, gallstones, pancreatic disorders. Pharmacology: PPIs, H2 blockers, laxatives, antiemetics.

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Embryology, hormones of the menstrual cycle, and pregnancy physiology. Pathologies: PCOS, endometriosis, infertility, gynecologic cancers. Include male reproductive pharmacology (androgens, anti-androgens).

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Review DSM-5 major disorders and drug classes. Understand mechanism of antidepressants, antipsychotics, anxiolytics. Include behavioral science and doctor-patient ethics.

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Core formulas: sensitivity, specificity, PPV, NPV, likelihood ratios. Understand bias types, study designs, and interpreting p-values & confidence intervals. Use question practice to strengthen application.

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Pathways: glycolysis, TCA, oxidative phosphorylation, urea cycle. Master enzyme deficiencies and vitamin cofactor roles. Integrate with molecular biology (DNA replication, transcription, translation).

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A complete system-based review of all pathology concepts covered in UWorld. This section focuses on disease mechanisms, key histopathological findings, and high-yield diagnostic clues tested on the USMLE. Each topic integrates pathophysiology with clinical correlations, helping students master disease patterns and identify the most tested features from UWorld question explanations.

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Comprehensive review of high-yield medical genetics — covering inheritance patterns, chromosomal disorders, mutations, gene mapping, and molecular techniques frequently tested on Step 1 and Step 2. Includes detailed explanations with clinical correlations and UWorld-based question discussions.

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Systematic and easy-to-grasp coverage of pharmacokinetics, pharmacodynamics, drug mechanisms, side effects, and contraindications. Each class of drug is broken down with UWorld-style reasoning and key mnemonics for rapid recall during exams.

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Step-oriented lectures covering bioethics principles, patient confidentiality, consent, end-of-life care, and cultural sensitivity. Includes common UWorld-type ethical scenarios to strengthen your decision-making for exam vignettes.

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Master every concept tested on the USMLE Step 1 with the NextGen USMLE UWorld Mastery Program a complete, structured video library covering all 3,600+ UWorld MCQs. Each question is explained in depth by U.S.-based residents and physicians, focusing on high-yield reasoning, first principles, and clinical correlations.Through this course, you’ll learn how to approach each question strategically, eliminate confusion, and strengthen your integration of Pathology, Pharmacology, Physiology, and Biochemistry all directly aligned with UWorld, First Aid, and Pathoma.Key Highlights:Full coverage of entire UWorld Step 1 QBank (all systems and subjects) Taught by U.S. medical residents and mentors Integrated explanations with First Aid and Pathoma references Access to recorded, high-yield discussions anytimePerfect for both independent review and guided 120-Day Marathon studentsOutcome: By the end of this program, you will have a complete command over the UWorld question bank — ready to tackle NBMEs and the Step 1 exam with confidence.
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$90

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USMLE Step 1 — MCQ’s

 

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$135

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 USMLE Step 1 — MCQ’s + Videos

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Premium

$250

/5 Month

USMLE Step 1 — MCQ’s + Videos + Notes
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/4 Month

USMLE Step 1 — MCQ’s + Videos + Notes + Online Classes
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STUDENT FEEDBACK

Hear what our students are saying

“This program completely changed how I use UWorld. Instead of memorizing answers, I finally understood why each option was right or wrong. The explanations from U.S. residents made complex concepts feel logical and manageable.”
Sarah Johnson

The Data Science course equipped me with the skills needed to excel in my career.

David Lee
“The biggest value was learning how to think. Every question was broken down step by step, just like on the real exam. This course turned UWorld into a true learning tool instead of just a question bank.”
Emily White
“I loved how closely the explanations were tied to First Aid and Pathoma. I could pause the video, annotate my book, and instantly connect concepts. It saved me months of scattered studying.”
Michael Brown
“As someone who struggled with biochemistry and pharmacology, this program was a game changer. The instructors explained everything from first principles, not shortcuts, which finally made things stick.”
Jessica Adams
“The 120-Day Marathon structure kept me accountable and consistent. Having guided access to every UWorld question explanation gave me confidence that nothing was left uncovered.”
William Smith
“This is the most comprehensive UWorld review I’ve ever seen. Every system, every subject, explained clearly by physicians who actually understand how Step 1 tests reasoning.”
Olivia Martinez
“I went from feeling overwhelmed by UWorld to feeling excited to solve questions. The strategic approach taught in this program helped me eliminate wrong choices faster and think clinically.”
James Wilson
Absolutely fantastic course
“By the end of this course, UWorld felt mastered—not feared. I walked into my NBME exams calm and confident, knowing I had built a strong foundation aligned perfectly with Step 1.”
Laura Davis
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Subscribe to any plan and instantly unlock all included content. You can study anytime, from any device.
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